Sox6 up-regulation by macrophage migration inhibitory factor promotes survival and maintenance of mouse neural stem/progenitor cells.
Macrophage migration inhibitory factor (MIF) has important roles in supporting the proliferation and/or survival of murine neural stem/progenitor cells (NSPCs), but downstream effectors remain unknown.We show here that MIF robustly increases the expression of Sox6 in NSPCs in vitro.During neural development, Sox6 is expressed in the ventricular zon